Articles tagged with: protein
Mutant prions help cells foil harmful protein misfolding Misfolded proteins are implicated in many incurable neurological diseases. A new and improved understanding of how naturally occurring variants keep proteins from bunching up and spreading provides more options for developing a treatment than scientists had realized. Mutant prions help cells The red color of the the […]
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Human protein improves muscle function of muscular dystrophy mice Now headed toward human trials, biglycan significantly slows the weakening of muscles in mice with the genetic mutation that causes muscular dystrophy. Biglycan causes utrophin, a natural muscle-building protein prevalent in young children, to collect in muscle cell membranes. PROVIDENCE, R.I. [Brown University] — A novel […]
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Research provides new leads in the case against drug-resistant biofilms Films of bacteria that form around foreign materials in the body can be very difficult to defeat with drugs, but research led by Brown University biologists has identified a couple proteins that play a key role in building these “biofilms.” This pair could prove to […]
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Size of protein aggregates, not abundance, drives spread of prion-based disease In a study that challenges the conventional wisdom about infections caused by proteins called prions, Brown researchers report in Science that the size of protein structures, rather than their abundance, determines their transmission among cells. PROVIDENCE, R.I. [Brown University] — Mad Cow disease and […]
